Welcome to the CLL proteome explorer app. This interactive shiny app will help you explore the CLL proteomic dataset and its associations to other multi-omics datasets included in the publication 'The Protein Landscape of Chronic Lymphocytic Leukemia (CLL)' by Meier-Abt and Lu et al.
In this panel, you can identify and visualize differentially expressed (DE) proteins related to a genomic feature (gene mutation or copy number variation) or demographic feature (sex). The DE list can be used for analyses (e.g enrichment analysis) in other panels.
In this panel, you can perform gene set enrichment analysis on the list of the DE proteins generated in the [Genomic association] panel, to investigate the potential pathway activity changes.
In this panel, you can plot the heatmap of the expression of a list of proteins, specificed in the [Plotting paramters] section to visuaize the protein expression variations among samples
In this panel, you can explore the associations between protein expressions and drug response phenotypes